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As a country with a high incidence of digestive diseases, chronic gastritis, gastroesophageal reflux, peptic ulcer, ulcerative colitis, alcoholic/non-alcoholic liver disease and other diseases have become common problems affecting national health.
In recent years, with its excellent biological activity, SFN has made significant breakthroughs in research in the field of treatment and adjuvant treatment of digestive system diseases, providing a new direction for the prevention and treatment of related diseases [1].
A large number of studies have confirmed that radish sulfine plays a key role in the protection of multiple digestive organs such as gastrointestinal tract, liver, pancreas and spleen through antioxidant, anti-inflammatory and other activities, providing scientific support for the intervention of a variety of digestive system diseases.
Helicobacter pylori (Hp) infection is very common in life and can often cause chronic gastritis, which in turn leads to gastric ulcer, duodenal ulcer, mucosal-related lymphatic tissue lymphoma and gastric cancer.
In a clinical trial of 110 Hp-infected cases, it was found that after eating broccoli seed water extract containing radish thionin (SFN) every day for two consecutive months, the level of inflammatory cytokines (mainly IL-8 and IFN-γ) in the infected body was significantly reduced, and the risk of gastric mucosal lesions was effectively reduced. Thus preventing Hp-induced gastric cancer (ChiCTR2100054249) [2].
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder associated with obesity and type 2 diabetes. In recent years, the research and related targets on the treatment of NAFLD by sfin (SFN) have increased rapidly. Studies show that radiothion intervention can significantly improve the excessive fat deposition of fatty liver mice induced by high-fat diet, while regulating the inflammatory response and antioxidant levels of the liver and serum [3].
Cell damage caused by alcohol mainly involves lipid peroxidation and oxidative stress. Studies show that there may be a relationship between alcoholic liver disease and oxidative stress. Experiments have confirmed that aerobic exercise combined with aerobic exercise can play a significant role in liver protection by inhibiting lipid peroxidation, providing a new path for the repair of alcoholic liver injury [4].
In the leucan-induced acute pancreatitis mouse model, radiothione (SFN) pretreatment can significantly reduce pancreatic edema, reduce serum amylase and medullary peroxidase (MPO) activity, and improve tissue damage [5].
Radish thionin (SFN) can enhance the cytokine secretion ability of spleen macrophages stimulated by LPS, significantly increasing the level of key factors such as IL-6, IL-10 and MCP-1, helping to restore some immune function of the spleen and supporting the maintenance of immune balance in the digestive system [6].
In summary, sulfurine (SFN) has shown a protective effect on gastric ulcers, gastric tumors, gastrointestinal and liver damage caused by various drugs, digestive system damage caused by ischemia-reperfusion, and digestive system diseases such as alcoholic or non-alcoholic liver disease [1].
Radish thionin is generally found in the form of glucoraphanin (GLR) in cruciferous vegetables. Radish thioside is a natural "thioglucoside" compound in cruciferous vegetables. It has a long-term antioxidant effect and is degraded into radio thioside through intestinal flora or black mustard enzyme.
Jiuzhen Biological - Deep cultivation of broccoli extract GLR® Broc Pio® research and development and production, launching four categories of multi-specification products:
Product category | Specification details | Product features |
Water extract of broccoli seeds | Radish thioside 13%~20% | Good flavor, high solubility and clarity |
Solid drinks | Conversion rate 80% | High conversion rate and good stability |
Radish thione | 1%, 10% and 95% can also provide customized specifications. | Fast absorption and high activity |
Stable radish thione | Radish thione 1%, 10% | It can be stored at room temperature and has good stability. |
Choosing Jiuzhen Biological is not only to choose a "highly active and high-safe" raw material, but also to choose a set of "from source to terminal" quality assurance system. We will escort your product research and development with an extremely rigorous attitude, so that you can be more confident in your marketing promotion!
⭐ If you have any questions about raw material needs, sample trial or technical consultation, please contact us~
